Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function

Glucocorticoids signal through the glucocorticoid receptor (GR) and are administered clinically for a variety of situations, including inflammatory disorders, specific cancers, rheumatoid arthritis, and organ/tissue transplantation. However, glucocorticoid therapy is also associated with additional...

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Vydáno v:J Biol Chem
Hlavní autoři: Burke, Susan J., May, Amanda L., Noland, Robert C., Lu, Danhong, Brissova, Marcela, Powers, Alvin C., Sherrill, Elizabeth M., Karlstad, Michael D., Campagna, Shawn R., Stephens, Jacqueline M., Collier, J. Jason
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505588/
https://ncbi.nlm.nih.gov/pubmed/25851902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632190
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