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Frequency and Distribution of Single-Nucleotide Polymorphisms within mprF in Methicillin-Resistant Staphylococcus aureus Clinical Isolates and Their Role in Cross-Resistance to Daptomycin and Host Defense Antimicrobial Peptides

MprF is responsible for the lysinylation of phosphatidylglycerol (PG) to synthesize the positively charged phospholipid (PL) species, lysyl-PG (L-PG). It has been proposed that the single-nucleotide polymorphisms (SNPs) within the mprF open reading frame (ORF) are associated with a gain-in-function...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Bayer, Arnold S., Mishra, Nagendra N., Chen, Liang, Kreiswirth, Barry N., Rubio, Aileen, Yang, Soo-Jin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505294/
https://ncbi.nlm.nih.gov/pubmed/26055370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00970-15
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