A Simulation Study Reveals Lack of Pharmacokinetic/Pharmacodynamic Target Attainment in De-escalated Antibiotic Therapy in Critically Ill Patients

De-escalation of empirical antibiotic therapy is often included in antimicrobial stewardship programs in critically ill patients, but differences in target attainment when antibiotics are switched are rarely considered. The primary objective of this study was to compare the fractional target attainm...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey, De Waele, Jan J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505256/
https://ncbi.nlm.nih.gov/pubmed/26014946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00409-15
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