A Simulation Study Reveals Lack of Pharmacokinetic/Pharmacodynamic Target Attainment in De-escalated Antibiotic Therapy in Critically Ill Patients

De-escalation of empirical antibiotic therapy is often included in antimicrobial stewardship programs in critically ill patients, but differences in target attainment when antibiotics are switched are rarely considered. The primary objective of this study was to compare the fractional target attainm...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey, De Waele, Jan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505256/
https://ncbi.nlm.nih.gov/pubmed/26014946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00409-15
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