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Comparative Pharmacokinetics and Pharmacodynamic Target Attainment of Ertapenem in Normal-Weight, Obese, and Extremely Obese Adults

Little is known of the effects of obesity on ertapenem drug disposition and pharmacodynamics. Thirty healthy volunteers in three body mass index (BMI) groups (10 per group), normal weight (BMI, 18.5 to 24.9 kg/m(2)), class I-II obesity (BMI, 30 to 39.9 kg/m(2)), and class III obesity (BMI, ≥40 kg/m(...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, M., Nafziger, A. N., Drusano, G. L., Ma, L., Bertino, J. S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426983/
https://ncbi.nlm.nih.gov/pubmed/16569832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1222-1227.2006
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