Population Pharmacokinetics and Target Attainment of Ertapenem in Plasma and Tissue Assessed via Microdialysis in Morbidly Obese Patients after Laparoscopic Visceral Surgery

Ertapenem provides broad-spectrum activity against many pathogens, and its use is relevant for the prophylaxis and treatment of infections in morbidly obese patients undergoing surgery. However, its pharmacokinetics and tissue penetration in these patients are not well defined. We assessed the popul...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wittau, Mathias, Paschke, Stephan, Kurlbaum, Max, Scheele, Jan, Ly, Neang S., Hemper, Evelyn, Kornmann, Marko, Henne-Bruns, Doris, Bulitta, Jürgen B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192102/
https://ncbi.nlm.nih.gov/pubmed/27795367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00952-16
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