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Population Pharmacokinetics and Target Attainment of Ertapenem in Plasma and Tissue Assessed via Microdialysis in Morbidly Obese Patients after Laparoscopic Visceral Surgery

Ertapenem provides broad-spectrum activity against many pathogens, and its use is relevant for the prophylaxis and treatment of infections in morbidly obese patients undergoing surgery. However, its pharmacokinetics and tissue penetration in these patients are not well defined. We assessed the popul...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Wittau, Mathias, Paschke, Stephan, Kurlbaum, Max, Scheele, Jan, Ly, Neang S., Hemper, Evelyn, Kornmann, Marko, Henne-Bruns, Doris, Bulitta, Jürgen B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192102/
https://ncbi.nlm.nih.gov/pubmed/27795367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00952-16
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