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Population Pharmacokinetics and Target Attainment of Meropenem in Plasma and Tissue of Morbidly Obese Patients after Laparoscopic Intraperitoneal Surgery

Meropenem serves as a clinically important, broad-spectrum antibiotic. While meropenem is commonly used in obese patients, its pharmacokinetics in this patient group is not well known. Our aim was to characterize the population pharmacokinetics and target attainment in plasma, subcutaneous tissue, a...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Wittau, Mathias, Scheele, Jan, Kurlbaum, Max, Brockschmidt, Claas, Wolf, Anna M., Hemper, Evelyn, Henne-Bruns, Doris, Bulitta, Jürgen B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576127/
https://ncbi.nlm.nih.gov/pubmed/26248353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00259-15
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