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Population Pharmacokinetics and Target Attainment of Meropenem in Plasma and Tissue of Morbidly Obese Patients after Laparoscopic Intraperitoneal Surgery

Meropenem serves as a clinically important, broad-spectrum antibiotic. While meropenem is commonly used in obese patients, its pharmacokinetics in this patient group is not well known. Our aim was to characterize the population pharmacokinetics and target attainment in plasma, subcutaneous tissue, a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wittau, Mathias, Scheele, Jan, Kurlbaum, Max, Brockschmidt, Claas, Wolf, Anna M., Hemper, Evelyn, Henne-Bruns, Doris, Bulitta, Jürgen B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576127/
https://ncbi.nlm.nih.gov/pubmed/26248353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00259-15
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