Population Pharmacokinetics and Target Attainment of Ertapenem in Plasma and Tissue Assessed via Microdialysis in Morbidly Obese Patients after Laparoscopic Visceral Surgery

Ertapenem provides broad-spectrum activity against many pathogens, and its use is relevant for the prophylaxis and treatment of infections in morbidly obese patients undergoing surgery. However, its pharmacokinetics and tissue penetration in these patients are not well defined. We assessed the popul...

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Sparad:
Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Wittau, Mathias, Paschke, Stephan, Kurlbaum, Max, Scheele, Jan, Ly, Neang S., Hemper, Evelyn, Kornmann, Marko, Henne-Bruns, Doris, Bulitta, Jürgen B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192102/
https://ncbi.nlm.nih.gov/pubmed/27795367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00952-16
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