θ-Defensin RTD-1 improves insulin action and normalizes plasma glucose and FFA levels in diet-induced obese rats

Inflammation is implicated in metabolic abnormalities in obesity and type 2 diabetes. Because θ-defensins have anti-inflammatory activities, we tested whether RTD-1, a θ-defensin, improves metabolic conditions in diet-induced obesity (DIO). DIO was induced by high-fat feeding in obese-prone CD rats...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Oh, Young Taek, Tran, Dat, Buchanan, Thomas A., Selsted, Michael E., Youn, Jang H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504933/
https://ncbi.nlm.nih.gov/pubmed/25991648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00131.2015
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