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Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic Agents

BACKGROUND AND OBJECTIVES: Management of patients with breast cancer often fails because of inherent or acquired resistance to chemotherapy. BRUCE (BIR repeat containing ubiquitin-conjugating enzyme) is a member of the inhibitor of apoptosis protein (IAP) family. It has various cellular functions in...

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Detalhes bibliográficos
Publicado no:J Cancer Sci Ther
Main Authors: Garrison, Jason B, Ge, Chunmin, Che, Lixiao, Pullum, Derek A, Peng, Guang, Khan, Sohaib, Ben-Jonathan, Nira, Wang, Jiang, Du, Chunying
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504245/
https://ncbi.nlm.nih.gov/pubmed/26191375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-5956.1000335
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