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Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin
Conglobatin is an unusual C(2)-symmetrical macrodiolide from the bacterium Streptomyces conglobatus with promising antitumor activity. Insights into the genes and enzymes that govern both the assembly-line production of the conglobatin polyketide and its dimerization are essential to allow rational...
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| 發表在: | Chem Biol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4504003/ https://ncbi.nlm.nih.gov/pubmed/26091168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.05.010 |
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