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The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety
Ossamycin from Streptomyces hygroscopicus var. ossamyceticus is an antifungal and cytotoxic polyketide and a potent inhibitor of the mitochondrial ATPase. Analysis of a near-complete genome sequence of the ossamycin producer has allowed the identification of the 127-kbp ossamycin biosynthetic gene c...
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| Publicado en: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6490886/ https://ncbi.nlm.nih.gov/pubmed/31039188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215958 |
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