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Evidence for an iterative module in chain elongation on the azalomycin polyketide synthase

The assembly-line synthases that produce bacterial polyketide natural products follow a modular paradigm in which each round of chain extension is catalysed by a different set or module of enzymes. Examples of deviation from this paradigm, in which a module catalyses either multiple extensions or no...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Hong, Hui, Sun, Yuhui, Zhou, Yongjun, Stephens, Emily, Samborskyy, Markiyan, Leadlay, Peter F
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082578/
https://ncbi.nlm.nih.gov/pubmed/27829923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.206
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