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Autophagy-independent senescence and genome instability driven by targeted telomere dysfunction
Telomere dysfunction plays a complex role in tumorigenesis. While dysfunctional telomeres can block the proliferation of incipient cancer clones by inducing replicative senescence, fusion of dysfunctional telomeres can drive genome instability and oncogenic genomic rearrangements. Therefore, it is i...
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502814/ https://ncbi.nlm.nih.gov/pubmed/25751002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1017189 |
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