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Telomere dysfunction as a cause of genomic instability in Werner syndrome
Werner syndrome (WS) is a rare human premature aging disease caused by mutations in the gene encoding the RecQ helicase WRN. In addition to the aging features, this disorder is marked by genomic instability, associated with an elevated incidence of cancer. Several lines of evidence suggest that telo...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2007
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794219/ https://ncbi.nlm.nih.gov/pubmed/17284601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609410104 |
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