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The Terminal Telomeric DNA Sequence Determines the Mechanism of Dysfunctional Telomere Fusion
Mammalian telomeres consist of tandem DNA repeats that bind protective protein factors collectively termed shelterins. Telomere disruption typically results in genome instability induced by telomere fusions. For reasons that are unclear, the mechanism of telomere fusion varies depending on the means...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920734/ https://ncbi.nlm.nih.gov/pubmed/20670897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.020 |
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