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The Terminal Telomeric DNA Sequence Determines the Mechanism of Dysfunctional Telomere Fusion

Mammalian telomeres consist of tandem DNA repeats that bind protective protein factors collectively termed shelterins. Telomere disruption typically results in genome instability induced by telomere fusions. For reasons that are unclear, the mechanism of telomere fusion varies depending on the means...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stohr, Bradley A., Xu, Lifeng, Blackburn, Elizabeth H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920734/
https://ncbi.nlm.nih.gov/pubmed/20670897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.020
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