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Human Cancer Cells Harbor T-Stumps, a Distinct Class of Extremely Short Telomeres

Using a modified single telomere length analysis protocol (STELA) to clone and examine the sequence composition of individual human XpYp telomeres, we discovered a distinct class of extremely short telomeres in human cancer cells with active telomerase. We name them “t-stumps”, to distinguish them f...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Xu, Lifeng, Blackburn, Elizabeth H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2081152/
https://ncbi.nlm.nih.gov/pubmed/17964269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.005
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