Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy

BACKGROUND: Telomeres cap chromosome ends and protect the genome. We studied individual telomeres in live human cancer cells. In capturing telomere motions using quantitative imaging to acquire complete high-resolution three-dimensional datasets every second for 200 seconds, telomere dynamics were s...

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Bibliografiske detaljer
Main Authors: Wang, Xueying, Kam, Zvi, Carlton, Peter M, Xu, Lifeng, Sedat, John W, Blackburn, Elizabeth H
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585561/
https://ncbi.nlm.nih.gov/pubmed/19014413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-1-4
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