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Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors
Recombinant adeno-associated viruses (rAAV) are promising candidates for gene therapy approaches. The last two decades were particularly fruitful in terms of processes applied in the production and purification of this type of gene transfer vectors. This rapid technological evolution led to better y...
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| Pubblicato in: | Mol Ther Methods Clin Dev |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502676/ https://ncbi.nlm.nih.gov/pubmed/26207258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.24 |
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