Rapid, scalable, and low-cost purification of recombinant adeno-associated virus produced by baculovirus expression vector system

Recombinant adeno-associated viruses (rAAV) are largely used for gene transfer in research, preclinical developments, and clinical trials. Their broad in vivo biodistribution and long-term efficacy in postmitotic tissues make them good candidates for numerous gene transfer applications. Upstream pro...

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Bibliographic Details
Published in:Mol Ther Methods Clin Dev
Main Authors: Buclez, Pierre-Olivier, Dias Florencio, Gabriella, Relizani, Karima, Beley, Cyriaque, Garcia, Luis, Benchaouir, Rachid
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867670/
https://ncbi.nlm.nih.gov/pubmed/27226971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.35
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