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Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors

Recombinant adeno-associated viruses (rAAV) are promising candidates for gene therapy approaches. The last two decades were particularly fruitful in terms of processes applied in the production and purification of this type of gene transfer vectors. This rapid technological evolution led to better y...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Methods Clin Dev
Päätekijät: Dias Florencio, Gabriella, Precigout, Guillaume, Beley, Cyriaque, Buclez, Pierre-Olivier, Garcia, Luis, Benchaouir, Rachid
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502676/
https://ncbi.nlm.nih.gov/pubmed/26207258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.24
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