The TMAO Generating Enzyme Flavin Monooxygenase 3 is a Central Regulator of Cholesterol Balance

Circulating levels of the gut microbe-derived metabolite trimethylamine-N-oxide (TMAO) have recently been linked to cardiovascular disease (CVD) risk. Here we performed transcriptional profiling in mouse models of altered reverse cholesterol transport (RCT), and serendipitously identified the TMAO-g...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Warrier, Manya, Shih, Diana M., Burrows, Amy C., Ferguson, Daniel, Gromovsky, Anthony D., Brown, Amanda L., Marshall, Stephanie, McDaniel, Allison, Schugar, Rebecca C., Wang, Zeneng, Sacks, Jessica, Rong, Xin, de Aguiar Vallim, Thomas, Chou, Jeff, Ivanova, Pavlina T., Myers, David S., Brown, H. Alex, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Liu, Xiuli, Parini, Paolo, Tontonoz, Peter, Lusis, Aldon J., Hazen, Stanley L., Temel, Ryan E., Brown, J. Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501903/
https://ncbi.nlm.nih.gov/pubmed/25600868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.12.036
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky