The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 (FMO3) Regulates Obesity and the Beiging of White Adipose Tissue

Emerging evidence suggests that microbes resident in the human intestine represent a key environmental factor contributing to obesity-associated disorders. Here we demonstrate that the gut microbiota-initiated trimethylamine-N-oxide (TMAO)-generating pathway is linked to obesity and energy metabolis...

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Publicado no:Cell Rep
Main Authors: Schugar, Rebecca C., Shih, Diana M., Warrier, Manya, Helsley, Robert N., Burrows, Amy, Ferguson, Daniel, Brown, Amanda L., Gromovsky, Anthony D., Heine, Markus, Chatterjee, Arunachal, Li, Lin, Li, Xinmin S., Wang, Zeneng, Willard, Belinda, Meng, YongHong, Kim, Hanjun, Che, Nam, Pan, Calvin, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Morton, Richard E., Langefeld, Carl D., Das, Swapan K., Rudel, Lawrence L., Zein, Nizar, McCullough, Arthur J., Dasarathy, Srinivasan, Tang, W.H. Wilson, Erokwu, Bernadette O., Flask, Chris A., Laakso, Markku, Civelek, Mete, Naga Prasad, Sathyamangla V., Heeren, Joerg, Lusis, Aldons J., Hazen, Stanley L., Brown, J. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672822/
https://ncbi.nlm.nih.gov/pubmed/28636934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.077
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