The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 (FMO3) Regulates Obesity and the Beiging of White Adipose Tissue

Emerging evidence suggests that microbes resident in the human intestine represent a key environmental factor contributing to obesity-associated disorders. Here we demonstrate that the gut microbiota-initiated trimethylamine-N-oxide (TMAO)-generating pathway is linked to obesity and energy metabolis...

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Vydáno v:Cell Rep
Hlavní autoři: Schugar, Rebecca C., Shih, Diana M., Warrier, Manya, Helsley, Robert N., Burrows, Amy, Ferguson, Daniel, Brown, Amanda L., Gromovsky, Anthony D., Heine, Markus, Chatterjee, Arunachal, Li, Lin, Li, Xinmin S., Wang, Zeneng, Willard, Belinda, Meng, YongHong, Kim, Hanjun, Che, Nam, Pan, Calvin, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Morton, Richard E., Langefeld, Carl D., Das, Swapan K., Rudel, Lawrence L., Zein, Nizar, McCullough, Arthur J., Dasarathy, Srinivasan, Tang, W.H. Wilson, Erokwu, Bernadette O., Flask, Chris A., Laakso, Markku, Civelek, Mete, Naga Prasad, Sathyamangla V., Heeren, Joerg, Lusis, Aldons J., Hazen, Stanley L., Brown, J. Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672822/
https://ncbi.nlm.nih.gov/pubmed/28636934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.077
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