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Idiopathic Short Stature due to Novel Heterozygous Mutation of the Aggrecan Gene

BACKGROUND: Recently, whole exome sequencing identified heterozygous defects in the Aggrecan gene (ACAN) in three families with short stature and advanced bone age. OBJECTIVE: We report a novel frameshift mutation in ACAN in a family with dominantly inherited short stature, advanced bone age, and pr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Pediatr Endocrinol Metab
Päätekijät: Quintos, Jose Bernardo, Guo, Michael H., Dauber, Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501863/
https://ncbi.nlm.nih.gov/pubmed/25741789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jpem-2014-0450
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