Voluntary Exercise Can Ameliorate Insulin Resistance by Reducing iNOS-Mediated S-Nitrosylation of Akt in the Liver in Obese Rats

Voluntary exercise can ameliorate insulin resistance. The underlying mechanism, however, remains to be elucidated. We previously demonstrated that inducible nitric oxide synthase (iNOS) in the liver plays an important role in hepatic insulin resistance in the setting of obesity. In this study, we tr...

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Udgivet i:PLoS One
Main Authors: Tsuzuki, Takamasa, Shinozaki, Shohei, Nakamoto, Hideko, Kaneki, Masao, Goto, Sataro, Shimokado, Kentaro, Kobayashi, Hiroyuki, Naito, Hisashi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501761/
https://ncbi.nlm.nih.gov/pubmed/26172834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132029
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