iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53

Inflammation and apoptosis develop in skeletal muscle after major trauma, including burn injury, and play a pivotal role in insulin resistance and muscle wasting. We and others have shown that inducible nitric oxide synthase (iNOS), a major mediator of inflammation, plays an important role in stress...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakazawa, Harumasa, Chang, Kyungho, Shinozaki, Shohei, Yasukawa, Takashi, Ishimaru, Kazuhiro, Yasuhara, Shingo, Yu, Yong-Ming, Martyn, J. A. Jeevendra, Tompkins, Ronald. G., Shimokado, Kentaro, Kaneki, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242494/
https://ncbi.nlm.nih.gov/pubmed/28099528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170391
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