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Genetic and cellular dissection of the activation of AM14 rheumatoid factor B cells in a mouse model of lupus
The RF-specific AM14 tg BCR has been used as a model to dissect the mechanisms of B cell tolerance to ICs containing nucleic acids. We have shown previously that AM14 RF B cells break tolerance in the TC mouse model of lupus through the dual engagement of the AM14 BCR and TLR9. In this study, we sho...
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| Published in: | J Leukoc Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Leukocyte Biology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501674/ https://ncbi.nlm.nih.gov/pubmed/25957308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1A1214-576R |
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