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Acetaminophen induces JNK/p38 signaling and activates the caspase-9-3-dependent cell death pathway in human mesenchymal stem cells

Acetaminophen (APAP) is a widely used analgesic and antipyretic drug. Generally, the therapeutic dose of APAP is clinically safe, however, high doses of APAP can cause acute liver and kidney injury. Therefore, the majority of previous studies have focussed on elucidating the mechanisms of APAP-induc...

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Foilsithe in:Int J Mol Med
Main Authors: YIANG, GIOU-TENG, YU, YUNG-LUNG, LIN, KO-TING, CHEN, JEN-NI, CHANG, WEI-JUNG, WEI, CHYOU-WEI
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501662/
https://ncbi.nlm.nih.gov/pubmed/26096646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2254
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