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Vitamin C enhances anticancer activity in methotrexate-treated Hep3B hepatocellular carcinoma cells

Methotrexate (MTX) has been widely used for rheumatoid arthritis therapy for a long time. MTX is also used as an anticancer drug for various tumors. However, many studies have shown that high-dose MTX treatment for cancer therapy may cause liver and renal damage. Alhough the mechanisms involved in M...

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Main Authors: YIANG, GIOU-TENG, CHOU, PEI-LUN, HUNG, YU-TING, CHEN, JEN-NI, CHANG, WEI-JUNG, YU, YUNG-LUEN, WEI, CHYOU-WEI
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121419/
https://ncbi.nlm.nih.gov/pubmed/24969544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3289
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