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Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation

Acetaminophen (APAP), is a safe analgesic and antipyretic drug at therapeutic dose, and is widely used in the clinic. However, high doses of APAP can induce hepatotoxicity and nephrotoxicity. Most studies have focused on high-dose APAP-induced acute liver and kidney injury. So far, few studies have...

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Main Authors: YU, YUNG-LUEN, YIANG, GIOU-TENG, CHOU, PEI-LUN, TSENG, HSU-HUNG, WU, TSAI-KUN, HUNG, YU-TING, LIN, PEI-SHIUAN, LIN, SHU-YU, LIU, HSIAO-CHUN, CHANG, WEI-JUNG, WEI, CHYOU-WEI
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055434/
https://ncbi.nlm.nih.gov/pubmed/24682227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2014.2085
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