SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS

Mutations in ASXL1 are frequent in patients with myelodysplastic syndrome (MDS) and associated with adverse survival yet the molecular pathogenesis of ASXL1 mutations are not fully understood. Recently it has been found that deletion of Asxl1 or expression of C-terminal-truncating ASXL1 mutations (A...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Inoue, Daichi, Kitaura, Jiro, Matsui, Hirotaka, Hou, Hsin-An, Chou, Wen-Chien, Nagamachi, Akiko, Kawabata, Kimihito Cojin, Togami, Katsuhiro, Nagase, Reina, Horikawa, Sayuri, Saika, Makoto, Micol, Jean-Baptiste, Hayashi, Yasutaka, Harada, Yuka, Harada, Hironori, Inaba, Toshiya, Tien, Hwei-Fang, Abdel-Wahab, Omar, Kitamura, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501574/
https://ncbi.nlm.nih.gov/pubmed/25306901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.301
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados