Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)

Recent progress in high-speed sequencing technology has revealed that tumors harbor novel mutations in a variety of genes including those for molecules involved in epigenetics and splicing, some of which were not categorized to previously thought malignancy-related genes. However, despite thorough i...

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Detalhes bibliográficos
Publicado no:J Biochem
Main Authors: Kitamura, Toshio, Watanabe-Okochi, Naoko, Enomoto, Yutaka, Nakahara, Fumio, Oki, Toshihiko, Komeno, Yukiko, Kato, Naoko, Doki, Noriko, Uchida, Tomoyuki, Kagiyama, Yuki, Togami, Katsuhiro, Kawabata, Kimihito C., Nishimura, Koutarou, Hayashi, Yasutaka, Nagase, Reina, Saika, Makoto, Fukushima, Tsuyoshi, Asada, Shuhei, Fujino, Takeshi, Izawa, Yuto, Horikawa, Sayuri, Fukuyama, Tomofusa, Tanaka, Yosuke, Ono, Ryoichi, Goyama, Susumu, Nosaka, Tetsuya, Kitaura, Jiro, Inoue, Daichi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
JB Special Reviews—Cell Fate Decision, and its Underlying Molecular Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882650/
https://ncbi.nlm.nih.gov/pubmed/26590301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv114
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