Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)

Recent progress in high-speed sequencing technology has revealed that tumors harbor novel mutations in a variety of genes including those for molecules involved in epigenetics and splicing, some of which were not categorized to previously thought malignancy-related genes. However, despite thorough i...

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Dettagli Bibliografici
Pubblicato in:J Biochem
Autori principali: Kitamura, Toshio, Watanabe-Okochi, Naoko, Enomoto, Yutaka, Nakahara, Fumio, Oki, Toshihiko, Komeno, Yukiko, Kato, Naoko, Doki, Noriko, Uchida, Tomoyuki, Kagiyama, Yuki, Togami, Katsuhiro, Kawabata, Kimihito C., Nishimura, Koutarou, Hayashi, Yasutaka, Nagase, Reina, Saika, Makoto, Fukushima, Tsuyoshi, Asada, Shuhei, Fujino, Takeshi, Izawa, Yuto, Horikawa, Sayuri, Fukuyama, Tomofusa, Tanaka, Yosuke, Ono, Ryoichi, Goyama, Susumu, Nosaka, Tetsuya, Kitaura, Jiro, Inoue, Daichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
JB Special Reviews—Cell Fate Decision, and its Underlying Molecular Mechanisms
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882650/
https://ncbi.nlm.nih.gov/pubmed/26590301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv114
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