Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)

Recent progress in high-speed sequencing technology has revealed that tumors harbor novel mutations in a variety of genes including those for molecules involved in epigenetics and splicing, some of which were not categorized to previously thought malignancy-related genes. However, despite thorough i...

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Détails bibliographiques
Publié dans:J Biochem
Auteurs principaux: Kitamura, Toshio, Watanabe-Okochi, Naoko, Enomoto, Yutaka, Nakahara, Fumio, Oki, Toshihiko, Komeno, Yukiko, Kato, Naoko, Doki, Noriko, Uchida, Tomoyuki, Kagiyama, Yuki, Togami, Katsuhiro, Kawabata, Kimihito C., Nishimura, Koutarou, Hayashi, Yasutaka, Nagase, Reina, Saika, Makoto, Fukushima, Tsuyoshi, Asada, Shuhei, Fujino, Takeshi, Izawa, Yuto, Horikawa, Sayuri, Fukuyama, Tomofusa, Tanaka, Yosuke, Ono, Ryoichi, Goyama, Susumu, Nosaka, Tetsuya, Kitaura, Jiro, Inoue, Daichi
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
JB Special Reviews—Cell Fate Decision, and its Underlying Molecular Mechanisms
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882650/
https://ncbi.nlm.nih.gov/pubmed/26590301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv114
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