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The role of climate and out-of-Africa migration in the frequencies of risk alleles for 21 human diseases
BACKGROUND: Demography and environmental adaptation can affect the global distribution of genetic variants and possibly the distribution of disease. Population heterozygosity of single nucleotide polymorphisms has been shown to decrease strongly with distance from Africa and this has been attributed...
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| 出版年: | BMC Genet |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501093/ https://ncbi.nlm.nih.gov/pubmed/26170196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0239-3 |
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