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The role of climate and out-of-Africa migration in the frequencies of risk alleles for 21 human diseases

BACKGROUND: Demography and environmental adaptation can affect the global distribution of genetic variants and possibly the distribution of disease. Population heterozygosity of single nucleotide polymorphisms has been shown to decrease strongly with distance from Africa and this has been attributed...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Blair, Lily M., Feldman, Marcus W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501093/
https://ncbi.nlm.nih.gov/pubmed/26170196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0239-3
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