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Mechanisms and regulation of iron trafficking across the capillary endothelial cells of the blood-brain barrier

The transcellular trafficking of iron from the blood into the brain interstitium depends on iron uptake proteins in the apical membrane of brain microvascular capillary endothelial cells and efflux proteins at the basolateral, abluminal membrane. In this review, we discuss the three mechanisms by wh...

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Bibliografske podrobnosti
izdano v:Front Mol Neurosci
Main Authors: McCarthy, Ryan C., Kosman, Daniel J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500905/
https://ncbi.nlm.nih.gov/pubmed/26236187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2015.00031
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