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Mechanisms and regulation of iron trafficking across the capillary endothelial cells of the blood-brain barrier

The transcellular trafficking of iron from the blood into the brain interstitium depends on iron uptake proteins in the apical membrane of brain microvascular capillary endothelial cells and efflux proteins at the basolateral, abluminal membrane. In this review, we discuss the three mechanisms by wh...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: McCarthy, Ryan C., Kosman, Daniel J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500905/
https://ncbi.nlm.nih.gov/pubmed/26236187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2015.00031
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