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The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs
The POT1 protein plays a critical role in telomere protection and telomerase regulation. POT1 binds single-stranded 5’-TTAGGGTTAG-3’ and forms a dimer with the TPP1 protein. The dimer is recruited to telomeres, either directly or as part of the Shelterin complex. Human POT1 contains two Oligonucleot...
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| Publicado no: | Biochimie |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500675/ https://ncbi.nlm.nih.gov/pubmed/25934589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2015.04.015 |
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