The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs

The POT1 protein plays a critical role in telomere protection and telomerase regulation. POT1 binds single-stranded 5’-TTAGGGTTAG-3’ and forms a dimer with the TPP1 protein. The dimer is recruited to telomeres, either directly or as part of the Shelterin complex. Human POT1 contains two Oligonucleot...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biochimie
Asıl Yazarlar: Choi, Kyung H., Lakamp-Hawley, Amanda S., Kolar, Carol, Yan, Ying, Borgstahl, Gloria E.O., Ouellette, Michel M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500675/
https://ncbi.nlm.nih.gov/pubmed/25934589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2015.04.015
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