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Three recognition events at the branch-site adenine.

An adenosine at the branch site, the nucleophile for the first transesterification step of splicing, is nearly invariant in mammalian pre-mRNA introns. The chemical groups on the adenine base were varied systematically and assayed for formation of early spliceosome complexes and execution of the fir...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Query, C C, Strobel, S A, Sharp, P A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8635472/
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