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Three recognition events at the branch-site adenine.

An adenosine at the branch site, the nucleophile for the first transesterification step of splicing, is nearly invariant in mammalian pre-mRNA introns. The chemical groups on the adenine base were varied systematically and assayed for formation of early spliceosome complexes and execution of the fir...

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Detalles Bibliográficos
Autores principales: Query, C C, Strobel, S A, Sharp, P A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC450044/
https://ncbi.nlm.nih.gov/pubmed/8635472
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