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Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells

Cardiac pacemaking initiated by the sinus node is attributable to the interplay of several membrane currents. These include the depolarizing ‘funny current’ (I(f)) and the sodium-calcium exchanger current (I(NCX)). The latter is activated by ryanodine receptor (RyR)-mediated calcium (Ca(2+)) release...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Kapoor, Nidhi, Tran, Andrew, Kang, Jeanney, Zhang, Rui, Philipson, Kenneth D, Goldhaber, Joshua I
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500350/
https://ncbi.nlm.nih.gov/pubmed/25903031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270082
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