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Initiation of Embryonic Cardiac Pacemaker Activity by Inositol 1,4,5-Trisphosphate–dependent Calcium Signaling

In the adult, the heart rate is driven by spontaneous and repetitive depolarizations of pacemaker cells to generate a firing of action potentials propagating along the conduction system and spreading into the ventricles. In the early embryo before E9.5, the pacemaker ionic channel responsible for th...

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Detalhes bibliográficos
Main Authors: Méry, Annabelle, Aimond, Franck, Ménard, Claudine, Mikoshiba, Katsuhiko, Michalak, Marek, Pucéat, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087245/
https://ncbi.nlm.nih.gov/pubmed/15758029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-10-0883
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