Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors

The inositol 1,4,5-trisphosphate receptor (IP(3)R) in the endoplasmic reticulum mediates calcium signaling that impinges on intracellular processes. IP(3)Rs are allosteric proteins comprising four subunits that form an ion channel activated by binding of IP(3) at a distance. Defective allostery in I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hamada, Kozo, Terauchi, Akiko, Nakamura, Kyoko, Higo, Takayasu, Nukina, Nobuyuki, Matsumoto, Nagisa, Hisatsune, Chihiro, Nakamura, Takeshi, Mikoshiba, Katsuhiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183345/
https://ncbi.nlm.nih.gov/pubmed/25201980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409730111
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