Disruption of prostaglandin E2 receptor EP4 impairs urinary concentration via decreasing aquaporin 2 in renal collecting ducts

The antidiuretic hormone arginine vasopressin is a systemic effector in urinary concentration. However, increasing evidence suggests that other locally produced factors may also play an important role in the regulation of water reabsorption in renal collecting ducts. Recently, prostaglandin E2 (PGE2...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gao, Min, Cao, Rong, Du, Shengnan, Jia, Xiao, Zheng, Senfeng, Huang, Shizheng, Han, Qifei, Liu, Jia, Zhang, Xiaoyan, Miao, Yifei, Kang, Jihong, Gustafsson, Jan-Åke, Guan, Youfei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500247/
https://ncbi.nlm.nih.gov/pubmed/26100911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509565112
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