Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice

The farnesoid X receptor (FXR) is a ligand-activated transcription factor belonging to the nuclear receptor superfamily. FXR is mainly expressed in liver and small intestine, where it plays an important role in bile acid, lipid, and glucose metabolism. The kidney also has a high FXR expression level...

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Main Authors: Zhang, Xiaoyan, Huang, Shizheng, Gao, Min, Liu, Jia, Jia, Xiao, Han, Qifei, Zheng, Senfeng, Miao, Yifei, Li, Shuo, Weng, Haoyu, Xia, Xuan, Du, Shengnan, Wu, Wanfu, Gustafsson, Jan-Åke, Guan, Youfei
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926076/
https://ncbi.nlm.nih.gov/pubmed/24464484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323977111
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