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Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB(1)
G protein-coupled receptors (GPCRs) are surprisingly flexible molecules that can do much more than simply turn on G proteins. Some even exhibit biased signaling, wherein the same receptor preferentially activates different G-protein or arrestin signaling pathways depending on the type of ligand boun...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500223/ https://ncbi.nlm.nih.gov/pubmed/26100912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500895112 |
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