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Identification of Ponatinib and Other Known Kinase Inhibitors with Potent MEKK2 Inhibitory Activity
The kinase MEKK2 (MAP3K2) may play an important role in tumor growth and metastasis for several cancer types. Thus, targeting MEKK2 may represent a novel strategy for developing more effective therapies for cancer. In order to identify small molecules with MEKK2 inhibitory activity, we screened a co...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500090/ https://ncbi.nlm.nih.gov/pubmed/26056008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.06.029 |
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